| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SYK |
4-[(2S)-2-[1-(4-methoxyphenyl)acetamido]-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-[1-(1H-indol-3-yl)acetamido]-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
433000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
Phenylmalonic acid |
NA |
12000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
Carbanilide |
NA |
660000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
3-(4-Phosphonooxy-benzyl)-N-{1-[3-(4-trifluoromethyl-benzyl)-[1,2,4]oxadiazol-5-yl]-ethyl}-succinamic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[(4-Methoxy-3-trifluoromethyl-phenyl)-phenyl-(3-trifluoromethyl-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid |
NA |
212000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid |
NA |
6740000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{3-[Tris-(4-methoxy-phenyl)-methoxy]-propyl}-piperidine-3-carboxylic acid |
NA |
169000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[9-(4-Methoxy-phenyl)-9H-fluoren-9-yloxy]-ethyl}-piperidine-3-carboxylic acid |
NA |
142000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[Tris-(4-methoxy-phenyl)-methylsulfanyl]-ethyl}-piperidine-3-carboxylic acid |
NA |
142000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[(4-Methoxy-phenyl)-diphenyl-methoxy]-ethyl}-piperidine-3-carboxylic acid |
NA |
178000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
N-(1-Benzylpiperidin-4-yl)-2,3-dimethoxybenzamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
N-(1-benzylpiperidin-4-yl)-2,6-dichloropyridine-3-carboxamide |
NA |
405000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
2,4-dichloro-N-[1-(pyridin-3-ylmethyl)piperidin-4-yl]benzamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
2,4-dichloro-N-[1-(3-diethoxyphosphorylpropyl)piperidin-4-yl]benzamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
2,4-dichloro-N-[1-(pyridin-4-ylmethyl)piperidin-4-yl]benzamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
2,4-dichloro-N-[1-(3-cyanopropyl)piperidin-4-yl]benzamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
Tert-butyl 2-[4-[(2,4-dichlorobenzoyl)amino]piperidin-1-yl]acetate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
2,4-dichloro-N-(1-prop-2-ynylpiperidin-4-yl)benzamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |