| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| Slc6a11 |
(3R)-8-benzhydrylidene-1,2,3,4,6,7,9,9a-octahydroquinolizine-3-carboxylic acid |
NA |
3233000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
N-(1-benzylpiperidin-4-yl)-2-ethoxybenzamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
N-(4,4-Diphenyl-3-butenyl)nipecotic acid |
NA |
944000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid |
NA |
1990000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[(3-Fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl)-phenyl-methoxy]-ethyl}-piperidine-3-carboxylic acid |
NA |
198000 |
NA |
NA |
NA |
NA |
TTD |
| Slc6a11 |
1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid |
NA |
1080000 |
NA |
NA |
NA |
NA |
TTD |
| TAAR1 |
N,N-Dimethyl-2-(4-chlorophenyl)ethylamine |
NA |
NA |
NA |
630000 |
NA |
NA |
BindingDB|TTD |
| TAAR1 |
2-(4-Tert-butylphenyl)ethan-1-amine |
NA |
NA |
NA |
5112000 |
NA |
NA |
BindingDB|TTD |
| TAAR1 |
4-Nitrophenethylamine hydrochloride |
NA |
NA |
NA |
167386 |
NA |
NA |
BindingDB|TTD |
| TACR1 |
(2S,3S)-2-Benzhydryl-3-benzyloxy-1-aza-bicyclo[2.2.2]octane |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR1 |
(2S)-2-N-[(2R)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-(2-nitrophenyl)pyrrolidine-1,2-dicarboxamide |
NA |
274000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR1 |
2-amino-5-(benzenesulfonyl)-4-(4-nitrophenyl)-6-pyridin-2-yl-4H-pyran-3-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR1 |
N-[(4R)-3-cyano-5-(4-methylphenyl)sulfinyl-4-(4-nitrophenyl)-6-pyridin-2-yl-4H-pyran-2-yl]-2,2,2-trifluoroacetamide |
NA |
NA |
NA |
350000 |
NA |
NA |
BindingDB|TTD |
| TACR1 |
Acyl Aszonalenin |
170000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR1 |
methyl 6-acetamido-3-[[(2S)-1-[benzyl(methyl)amino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate |
158000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR1 |
5-{3,4,5-Tris-benzyloxy-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentylamine |
NA |
120000 |
NA |
NA |
NA |
NA |
BindingDB |
| TACR2 |
methyl 6-acetamido-3-[[(2S)-1-[benzyl(methyl)amino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate |
398000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR2 |
methyl 6-acetamido-3-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate |
3000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TACR2 |
[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-3-(1H-indol-3-yl)-2-[[(2S)-4-methyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]pentanoyl]amino]propanoate |
250000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TACR2 |
4-[(4-chlorophenyl)amino]-2-[4-[(2E)-2-hydroxyiminopropanoyl]piperazin-1-yl]-6-propan-2-yl-5H-pyrrolo[4,3-e]pyrimidin-7-one |
150000 |
NA |
NA |
NA |
NA |
NA |
GtoPDB |