| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
6-[(2-fluorophenyl)methylsulfanyl]-4-[[4-(hydroxymethyl)phenyl]methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
156600 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-[(3-chlorophenyl)methylsulfanyl]-6-[(2,6-difluorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
165600 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
6-[(5-cyclopropyl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]-2-N-(4-fluorophenyl)-1,3,5-triazine-2,4-diamine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-N-(4-fluorophenyl)-6-[(1-propylimidazol-2-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
6-[(5-Pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4,6-dichloro-N-(2-ethylphenyl)-1,3,5-triazin-2-amine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-[(4-methoxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
AesculiosideIV-23C1 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
kaempferol 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside |
NA |
600000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
21,22-O-Diangeloyl-3beta,16alpha,28-trihydroxyolean-12-ene |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
9-Desfluoro levofloxacin |
NA |
728000 |
NA |
NA |
NA |
NA |
BindingDB |
| TOP2A |
Camptothecin |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
Aesculioside IV-23E |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
3-[(2R,3S,4S)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one |
NA |
550000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[(3R,4S,5R)-3,4-dihydroxy-5-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-3-yl]oxyoxolan-3-yl]methyl acetate |
NA |
240000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Lupeol |
NA |
250000 |
NA |
NA |
NA |
NA |
PubChem |
| TOP2A |
2-N-(4-fluorophenyl)-6-[(1-methyltetrazol-5-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Ciprofloxacin |
NA |
256000|153600 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
AC1Mdxvq |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Olivetolic Acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |