| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
(3E)-3-[(4-hydroxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
327000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(E)-3-(3,4-Dihydroxybenzylidene)benzofuran-2(3H)-one |
NA |
272000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-[(3-hydroxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-benzylidene-5-hydroxy-1-benzofuran-2-one |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-[(4-hydroxy-3-methoxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
351000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIIf |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Gypenoside Xvii |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
6-(2,6-Dimethylpyridin-4-yl)-7-fluoro-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;hydrochloride |
NA |
NA |
NA |
560000 |
NA |
NA |
TTD |
| TOP2A |
7-(2,6-Dimethylpyridin-4-yl)-6,8-difluoro-4-oxothiochromene-3-carboxylic acid;hydrochloride |
NA |
NA |
NA |
140000 |
NA |
NA |
TTD |
| TOP2A |
6-(4-aminophenyl)-4-sulfanylidene-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[(4,6-Dichloro-1,3,5-triazin-2-yl)sulfanyl]benzoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
N-(2-tert-butylphenyl)-4,6-dichloro-1,3,5-triazin-2-amine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[2-[(4,6-Dichloro-1,3,5-triazin-2-yl)amino]phenyl]ethanol |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4,6-dichloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-1,3,5-triazin-2-amine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[(4,6-Dimethoxy-1,3,5-triazin-2-yl)amino]benzoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(2R)-2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)amino]pentanedioic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
dibenzyl (2R)-2-[[2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)sulfanyl]benzoyl]amino]pentanedioate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
dibenzyl (2R)-2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)amino]pentanedioate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
benzyl (2S)-2-[[4-methoxy-6-[2-[[(2S)-1-oxo-1-phenylmethoxypropan-2-yl]carbamoyl]anilino]-1,3,5-triazin-2-yl]amino]propanoate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Ginsenoside-F5 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |