| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
N-[(5S,5aS,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]-4-[3-(trifluoromethyl)diazirin-3-yl]benzamide |
NA |
114000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2, 3-Dihydroxy-12-ursen-28-oic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Lupeol 3-acetate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Ginsenoside F3 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
20(R)-Ginsenoside Rg2 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(20R)-Ginsenoside Rg3 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Quasipanaxatriol |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[(3R,4R,4aR,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-5,10-dihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-4-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IVa |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[(3R,4R,4aR,5S,6R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,6,10-trihydroxy-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-3-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4-yl] 2-methylbutanoate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IVc |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[(3R,4R,4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,10-dihydroxy-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-3-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4-yl] 2-methylbutanoate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IVb |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[(3R,4R,4aR,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-5,10-dihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-4-(2-methylpropanoyloxy)-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIIb |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIi |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Eryngiioside J |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Saniculasaponin III |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Eryngiioside L |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIg |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |