| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
Aesculioside IIk |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIIa |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIa |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Eryngioside 94A |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIc |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IId |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
21-Angeloyl-protoaescigenin |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Eryngioside F |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Eryngioside E |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIId |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIIe |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIj |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIf |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Aesculioside IIIc |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Quinovic acid 28-O-beta-D-glucopyranosyl ester |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
3-O-beta-6-deoxy-D-glucopyranosyl cincholic acid28-O-beta-D-glucopyranosyl ester |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
3-O-alpha-L-rhamnopyranosyl quinovic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-1,2,6b,9,9,12a-hexamethyl-4a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-4a-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxycarbonyl-1,2,6b,9,9,12a-hexamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
N-((4-(2-chlorophenyl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-3-methoxybenzamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |