| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
Guttiferone E |
NA |
101200 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-(2,4-Dihydroxybenzoyloxy)-2-hydroxybenzoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-[(4-chlorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
219300 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-(cyclohexylmethylsulfanyl)-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Novobiocin |
NA |
256000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
6-benzylsulfanyl-4-[(3-methoxyphenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
485300 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-[(4-methoxyphenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-[(4-fluorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
146600 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-[(2-nitrophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
376700 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
6-benzylsulfanyl-4-[(3-nitrophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
488300 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-[(4-nitrophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
358900 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[(4-benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanylmethyl]benzonitrile |
NA |
522000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
3-[(2-benzylsulfanyl-6-oxo-1H-1,3,5-triazin-4-yl)sulfanylmethyl]benzonitrile |
NA |
528000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-[(4-benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanylmethyl]benzonitrile |
NA |
153400 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-[(4-benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanylmethyl]-3-fluorobenzonitrile |
NA |
485800 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-propylsulfanyl-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-butylsulfanyl-1H-1,3,5-triazin-2-one |
NA |
234700 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-(cyclopropylmethylsulfanyl)-1H-1,3,5-triazin-2-one |
NA |
481000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-6-(cyclobutylmethylsulfanyl)-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[[4-Chloro-6-[(4-methoxyphenyl)methylamino]-1,3,5-triazin-2-yl]-methylamino]ethanol |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |