| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
4-benzylsulfanyl-6-[(2-methoxyphenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[2-[[4-Chloro-6-[2-hydroxyethyl(methyl)amino]-1,3,5-triazin-2-yl]amino]phenyl]ethanol |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
6-benzylsulfanyl-4-sulfanylidene-1H-1,3,5-triazin-2-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[(4,6-Dimethoxy-1,3,5-triazin-2-yl)sulfanyl]benzoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Kaempferol 3-O-Alpha-L-Arabinopyranosyl-7-O-Alpha-L-Rhamnopyranoside |
NA |
330000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Cholesterol |
NA |
500000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
2-[O-Carbomethoxyanilino]-4,6-dichloro-S-triazine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
methyl N-[[3-(ethylcarbamoylamino)-5-(2-methylpyridin-4-yl)isoquinolin-8-yl]methyl]carbamate |
NA |
256000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Cholestanol |
NA |
500000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
2-[(3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethylhexyl)-10,13-dimethylhexadecahydrocyclopenta[a]phenanthren-3-yloxy]ethanol |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Quinizarin |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
1-Ethyl-3-(8-methyl-5-pyridin-4-ylisoquinolin-3-yl)urea |
NA |
256000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
1-Ethyl-3-[5-(2-methylpyridin-4-yl)-8-[(6-methylpyridin-3-yl)amino]isoquinolin-3-yl]urea |
NA |
256000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
10-O-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 1-O-methyl decanedioate |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[(2-anilino-2-oxoethyl)amino]-7-oxoheptanoate |
NA |
149000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[[2-(4-hydroxyanilino)-2-oxoethyl]amino]-7-oxoheptanoate |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[[2-[4-(hydroxymethyl)anilino]-2-oxoethyl]amino]-7-oxoheptanoate |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[4-[[2-[[7-[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-7-oxoheptanoyl]amino]acetyl]amino]phenyl]acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
alpha-Amyrin |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Propan-2-yl 2-[[4-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzoyl]amino]propanoate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |