| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| WDR5 |
2-(3-propan-2-yloxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole |
109000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |
| WDR5 |
2-(4-butan-2-yloxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole |
125000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| WDR5 |
2-(3-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole |
117000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |
| WDR5 |
N-[3-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)phenyl]acetamide |
125000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| WDR5 |
N-[4-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)phenyl]acetamide |
118000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |
| WDR5 |
2-(3-Chlorophenoxy)ethanimidamide |
651000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |
| WDR5 |
[1,1'-Biphenyl]-4-carboximidamide |
843000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |
| WDR5 |
4-(2,3-Dihydroimidazo[2,1-b][1,3]thiazol-6-yl)phenol |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| WDR5 |
2-(4-Ethoxyphenyl)imidazo[1,2-a]pyridine |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| WDR5 |
2-Phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole |
323000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |
| WEE1 |
N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| WEE1 |
4-Phenyl-[1]benzofuro[2,3-b]pyridine-3,6-diol |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| WNT3A |
nonasodium;(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-5-acetamido-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-5-acetamido-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6S)-5-acetamido-4-hydroxy-6-pentoxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfonatooxyoxane-2-carboxylate |
NA |
NA |
250000000 |
NA |
NA |
NA |
BindingDB |
| WNT3A |
nonasodium;(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6S)-6-(5-aminopentoxy)-4-hydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfonatooxyoxane-2-carboxylate |
NA |
NA |
250000000 |
NA |
NA |
NA |
BindingDB |
| XDH |
(2S,3R,4R,5R,6R)-2-methyl-6-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenoxy]oxan-2-yl]methoxy]oxane-3,4,5-triol |
NA |
129000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| XDH |
(2R,3R,4R,5R,6S)-2-[[(2R,3S,4S,5R,6S)-3,4-dihydroxy-6-[3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenoxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methoxy]-6-methyloxane-3,4,5-triol |
NA |
178000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| XDH |
Fusarentin 6,7-dimethyl ether |
NA |
644000 |
NA |
NA |
NA |
NA |
TTD |
| XDH |
5-Methylbenzimidazole |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| XDH |
(5-hydroxy-1H-indol-2-yl)-[4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl]methanone |
NA |
200000000 |
NA |
NA |
NA |
NA |
BindingDB |
| XDH |
3-Hydroxycoumarin |
NA |
131000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |