| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| VEGFA |
[(2R,3R,4S,5S,6S)-2-[[[2-[acetyl-(4-butylcyclohexyl)amino]acetyl]amino]methyl]-6-methoxy-3,5-disulfonatooxyoxan-4-yl] sulfate |
NA |
NA |
1000000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
2-[acetyl-[2-[[(2R,3R,4S,5S,6S)-6-methoxy-3,4,5-trisulfonatooxyoxan-2-yl]methylamino]-2-oxoethyl]amino]ethyl sulfate |
NA |
NA |
280000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[2-[ethyl-[2-[[(2R,3R,4S,5S,6S)-6-methoxy-3,4,5-trisulfonatooxyoxan-2-yl]methylamino]-2-oxoethyl]amino]-2-oxoethyl] sulfate |
NA |
NA |
512000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
6-[ethyl-[2-[[(2R,3R,4S,5S,6S)-6-methoxy-3,4,5-trisulfonatooxyoxan-2-yl]methylamino]-2-oxoethyl]amino]-6-oxohexanoate |
NA |
NA |
104000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[10-[ethyl-[2-[[(2R,3R,4S,5S,6S)-6-methoxy-3,4,5-trisulfonatooxyoxan-2-yl]methylamino]-2-oxoethyl]amino]-10-oxodecyl] sulfate |
NA |
NA |
545000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[(2R,3R,4S,5S,6S)-2-[[[2-[benzoyl(ethyl)amino]acetyl]amino]methyl]-6-methoxy-3,5-disulfonatooxyoxan-4-yl] sulfate |
NA |
NA |
1100000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[(2R,3R,4S,5S,6S)-2-(azidomethyl)-6-methoxy-3,5-disulfonatooxyoxan-4-yl] sulfate |
NA |
NA |
630000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[(2R,3R,4S,5S,6S)-2-[[[2-[acetyl(cycloheptyl)amino]acetyl]amino]methyl]-6-methoxy-3,5-disulfonatooxyoxan-4-yl] sulfate |
NA |
NA |
3000000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
4-[ethyl-[2-[[(2R,3R,4S,5S,6S)-6-methoxy-3,4,5-trisulfonatooxyoxan-2-yl]methylamino]-2-oxoethyl]amino]-4-oxobutanoate |
NA |
NA |
207000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[(2S,3S,4S,5R,6R)-2-[2-[[2-(N-acetylanilino)acetyl]amino]ethoxy]-3,5-disulfonatooxy-6-(sulfonatooxymethyl)oxan-4-yl] sulfate |
NA |
NA |
402000 |
NA |
NA |
NA |
BindingDB |
| VEGFA |
[(2R,3R,4S,5S,6S)-2-[[[2-[ethyl(3-phenylpropanoyl)amino]acetyl]amino]methyl]-6-methoxy-3,5-disulfonatooxyoxan-4-yl] sulfate |
NA |
NA |
596000 |
NA |
NA |
NA |
BindingDB |
| VHL |
(4r)-1-Acetyl-4-Hydroxy-N-Methyl-L-Prolinamide |
NA |
NA |
4900000 |
NA |
NA |
NA |
ChEMBL |
| VHL |
6-Chlorothiochroman-4-one |
NA |
NA |
6700000 |
NA |
NA |
NA |
BindingDB |
| VHL |
(2s,4r)-N-Methyl-1-[2-(3-Methyl-1,2-Oxazol-5-Yl)ethanoyl]-4-Oxidanyl-Pyrrolidine-2-Carboxamide |
NA |
NA |
240000 |
NA |
NA |
NA |
ChEMBL |
| VHL |
[4-(1H-Pyrrol-1-yl)phenyl]methanol |
NA |
NA |
5000000 |
NA |
NA |
NA |
BindingDB |
| VHL |
(2s,4r)-1-Ethanoyl-N-[[4-(1,3-Oxazol-5-Yl)phenyl]methyl]-4-Oxidanyl-Pyrrolidine-2-Carboxamide |
NA |
NA |
150000 |
NA |
NA |
NA |
ChEMBL |
| VHL |
2-(3-methyl-1,2-oxazol-5-yl)-N-propan-2-ylacetamide |
NA |
NA |
4300000 |
NA |
NA |
NA |
ChEMBL |
| VHL |
N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]acetamide |
NA |
NA |
2700000 |
NA |
NA |
NA |
ChEMBL |
| VRK1 |
N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine |
NA |
129000 |
NA |
NA |
NA |
NA |
BindingDB |
| WDR5 |
2-(4-Methylphenoxy)acetamidine |
589000 |
NA |
NA |
NA |
NA |
NA |
ChEMBL|TTD |