| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACR |
N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-phenyl-1H-pyrazole-5-carboxamide |
NA |
940000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACR |
N-(6-bromo-1,3-benzothiazol-2-yl)-2-(dibutylamino)acetamide |
NA |
2780000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACR |
N-((1S)-5-amino-1-(chloroacetyl)pentyl)-4-methylbenzenesulfonamide |
NA |
142600000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACR |
Ethyl 5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate |
NA |
240000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACVR1 |
1Kks7U3X86 |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem |
| ACVR1 |
N-(3-Carbamoylbenzyl)-1-cyclopentyl-2-(isoquinolin-6-yl)-1H-benzo[d]imidazole-6-carboxamide |
NA |
124000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACVR1 |
N-[(3-carbamoylphenyl)methyl]-2-isoquinolin-6-yl-3-[(1R,3R)-3-(methylcarbamoyl)cyclopentyl]benzimidazole-5-carboxamide |
NA |
251000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACVR1B |
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline |
NA |
265000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACVRL1 |
N-(3-Carbamoylbenzyl)-1-cyclopentyl-2-(isoquinolin-6-yl)-1H-benzo[d]imidazole-6-carboxamide |
NA |
131000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACVRL1 |
N-[(3-carbamoylphenyl)methyl]-2-isoquinolin-6-yl-3-[(1R,3R)-3-(methylcarbamoyl)cyclopentyl]benzimidazole-5-carboxamide |
NA |
267000 |
NA |
NA |
NA |
NA |
BindingDB |
| ADA |
3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-nonan-2-ol |
180000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADA |
1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-carboxamide |
5900000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADA |
(3R,4S,5R)-2-(4-aminotriazolo[4,5-d]pyridazin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
1410000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADA |
Adenosine |
2180000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem|TTD |
| ADAM10 |
(1S,2R)-2-cyano-N-hydroxy-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADAM10 |
(1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADAM10 |
(1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)-2-N-hydroxycyclopropane-1,2-dicarboxamide |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADAM10 |
(1R,2S)-1-(3-fluoro-4-((2-phenylquinolin-4-yl)methoxy)benzyl)-N2-hydroxy-N1,N1-dimethylcyclopropane-1,2-dicarboxamide |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADAM10 |
(1S,2R)-N-hydroxy-2-((S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl)-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADAM10 |
(1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |