| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADAM10 |
(1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate |
10000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADAM17 |
Apratastat |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |
| ADAM17 |
2-[2-[4-[3-(1,3-dioxoisoindol-2-yl)propoxy]phenyl]sulfonylphenyl]-N-hydroxyacetamide |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| ADAM17 |
2-[(5-bromothiophen-2-yl)sulfonyl-propan-2-yloxyamino]-N-hydroxyacetamide |
NA |
114000 |
NA |
NA |
NA |
NA |
TTD |
| ADAM17 |
2-{isopropoxy[(4-methoxyphenyl)sulfonyl]amino}-N-hydroxyacetamide |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| ADAM17 |
(2S,5S)-N,5-dihydroxy-1-(4-(2-iodobenzyloxy)phenylsulfonyl)piperidine-2-carboxamide |
NA |
110000 |
NA |
NA |
NA |
NA |
TTD |
| ADAM17 |
GI254023X |
NA |
541000 |
NA |
NA |
NA |
NA |
GtoPDB |
| ADAMTS4 |
H-Cys-Thr-Glu-Ala-Ser-Glu-Ser-Leu-Ala-Gly-Cys-OH |
NA |
120000 |
NA |
NA |
NA |
NA |
BindingDB |
| ADAMTS4 |
N-[(2s,4s)-1-({4-[2-(3,5-Dimethyl-1,2-Oxazol-4-Yl)ethyl]piperidin-1-Yl}sulfonyl)-4-(5-Fluoropyrimidin-2-Yl)-2-Methylpentan-2-Yl]-N-Hydroxyformamide |
NA |
25118864 |
NA |
NA |
NA |
NA |
BindingDB |
| ADAMTS4 |
(2R)-2-[[4-[3-(acetamidomethyl)phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADAMTS4 |
(2R)-2-[[4-[4-[[acetyl(methyl)amino]methyl]phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
{[2-(6-Amino-purin-9-yl)-ethyl]-tert-butoxycarbonyl-amino}-acetic acid methyl ester |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
(1R,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
(1R,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
(1S,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
(1R,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
(1S,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarboxylic acid hydroxyamide |
NA |
188000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADCY5 |
(1R,3S)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarboxylic acid hydroxyamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
5-(6-Aminopurin-9-yl)pentanoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ADCY5 |
7-(6-Amino-purin-9-yl)-heptanoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |