| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| APEX1 |
3-(4-Ethylphenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(4-(trifluoromethoxy)phenyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(m-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1-Cyclopropyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-(4-Ethylphenyl)-6-methyl-1-propylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-(4-Ethylphenyl)-6-methyl-1-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1-Benzyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-(4-Ethylphenyl)-1-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-(4-Ethylphenyl)-1-methyl-6-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
6-Benzyl-3-(4-ethylphenyl)-1-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-Cyclopentyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(oxan-4-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(naphthalen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(1,3-thiazol-4-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(4-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1,6-Dimethyl-3-(4-phenylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
1-Ethyl-3-(4-ethylphenyl)-6-methylpyrimido[4,5-c]pyridazine-5,7-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
6-(4-Ethylphenyl)-1,3-dimethylpteridine-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
7-Amino-1-methyl-3-(4-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazin-5-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |