| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| APEX1 |
N-[4-(3,4-dimethoxyphenyl)thiophen-2-yl]-1-methyl-6-oxo-5-phenylmethoxypyrimidine-4-carboxamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
[1-[4-(3,4-Dimethoxyphenyl)thiophene-2-carbonyl]piperidin-3-yl]-dimethoxyphosphorylmethanone |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
3-[4-(3,4-dimethoxyphenyl)thiophen-2-yl]-N-methylsulfonylbenzamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
4-[4-(3,4-dimethoxyphenyl)thiophen-2-yl]-N-methylsulfonylbenzamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
9-Chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
7-Chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-methylpyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-cyclopropylpyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-cyclohexylpyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-piperidin-4-ylpyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-(4-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-(4-methoxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-(3-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
8-Chloro-10-(2-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
10-Phenyl-8-(trifluoromethyl)pyrimido[4,5-b]quinoline-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
2,4-Dioxo-10-phenylpyrimido[4,5-b]quinoline-8-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
10-(3-Hydroxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
10-(4-Hydroxyphenyl)-2,4-Dioxo-2,3,4,10-Tetrahydropyrimido[4,5-B]quinoline-8-Carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
10-[3-(Hydroxymethyl)phenyl]-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| APEX1 |
10-(3-Methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |