| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| APP |
4-Chloro-5-(methylsulfamoyl)-2-(oxolan-2-ylmethylamino)benzoic acid |
NA |
136390 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
2,4-dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-9-oxododeca-2,6,10-trienyl]benzoic acid |
NA |
150800 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
(E)-1-(3,3-difluoroazetidin-1-yl)-3-(3-methoxy-4-phenylmethoxyphenyl)prop-2-en-1-one |
NA |
106820 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
1-[[4-(3-Piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione |
NA |
NA |
1547000 |
NA |
NA |
NA |
BindingDB |
| APP |
(3S,6S)-3-benzyl-6-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione |
NA |
NA |
12000000 |
NA |
NA |
NA |
BindingDB |
| APP |
2-[4-[(E)-2-[6-(dibutylamino)naphthalen-2-yl]ethenyl]quinolin-1-ium-1-yl]ethanol;chloride |
NA |
NA |
245925|489800|847500|1086000 |
NA |
NA |
NA |
BindingDB |
| APP |
9-[2-(2-methoxyethoxy)ethyl]-3-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]carbazole;iodide |
NA |
NA |
194000 |
NA |
NA |
NA |
BindingDB |
| APP |
N,N-dibutyl-6-[(E)-2-(1-methylquinolin-1-ium-4-yl)ethenyl]naphthalen-2-amine;iodide |
NA |
NA |
127600|246300|280800 |
NA |
NA |
NA |
BindingDB |
| APP |
N,N-dibutyl-6-[(E)-2-(2-methylisoquinolin-2-ium-4-yl)ethenyl]naphthalen-2-amine;iodide |
NA |
NA |
1109000 |
NA |
NA |
NA |
BindingDB |
| APP |
H-Ser-Tyr-Ser-Thr-Pro-Gly-Lys-OH |
NA |
NA |
650000 |
NA |
NA |
NA |
BindingDB |
| APP |
4-[[[2-[[(2-Oxochromen-4-yl)iminohydrazinylidene]-diphenyl-lambda5-phosphanyl]ethyl-diphenyl-lambda5-phosphanylidene]amino]diazenyl]chromen-2-one |
NA |
337770 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
H-Trp-Aib-His-OH |
NA |
NA |
5740000 |
NA |
NA |
NA |
BindingDB |
| APP |
2-[(E)-2-[1-[[2-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-2H-pyridin-4-yl]ethenyl]quinolin-8-ol;hydrochloride |
NA |
1655000 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
Latrepirdine |
NA |
NA |
NA |
25000000 |
NA |
NA |
BindingDB|PubChem|TTD |
| APP |
Donepezil |
NA |
1593000 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| APP |
Flurbiprofen |
NA |
305000 |
NA |
NA |
NA |
NA |
BindingDB|PubChem|TTD |
| APP |
Ferulic acid |
NA |
226230 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| APP |
3-Phenylpropionic acid, 2-phenylethyl ester |
NA |
NA |
NA |
4536000 |
NA |
NA |
BindingDB|TTD |
| APP |
Quercetin |
NA |
124600 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| APP |
Apigenin |
NA |
176200 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |