| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| APP |
5-[1-(2-Fluoro-4''-trifluoromethyl-biphenyl-4-yl)-ethyl]-1H-tetrazole |
NA |
114000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| APP |
1-[3-Fluoro-4-[4-(4-hydroxyphenyl)phenyl]phenyl]cyclopropane-1-carboxylic acid |
NA |
409000 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
Aromadendrin |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| APP |
(1S,5R,7R,9S,11R)-2',2',5,10,10,13-hexamethylspiro[3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane-11,9'-7H-[1,4]dioxepino[2,3-f]indole]-4,8',14-trione |
NA |
NA |
NA |
300000 |
NA |
NA |
TTD |
| APP |
Paraherquamide K |
NA |
NA |
NA |
300000 |
NA |
NA |
TTD |
| APP |
29-N-demethylparaherquamide J |
NA |
NA |
NA |
300000 |
NA |
NA |
TTD |
| APP |
29-N-demethylparaherquamide K |
NA |
244300 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
16-deoxo-paraherquamide J |
NA |
NA|269500 |
NA |
105200|NA |
NA |
NA |
BindingDB|TTD |
| APP |
(1'S,3R,5'R,7'S,9'S)-5',7,7,10',10',13'-hexamethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,14'-dione |
NA |
203700 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| APP |
Brevione L |
NA |
NA |
NA |
300000 |
NA |
NA |
TTD |
| APP |
(1'S,3R,7'S,9'S)-7,7,10',10',13'-pentamethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,4',14'-trione |
NA |
NA|186600 |
NA |
149600|NA |
NA |
NA |
BindingDB |
| APP |
(E)-N,N-diethyl-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide |
NA |
205460 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
2-(3,4-Dimethoxyphenyl)ethyl 3-phenylpropanoate |
NA |
NA |
NA |
274000 |
NA |
NA |
BindingDB|TTD |
| APP |
(E)-3-(3,4-dihydroxyphenyl)-N,N-diethylprop-2-enamide |
NA |
119160 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
2,2,2-Trifluoro-1-[4-fluoro-2-(furan-2-ylmethylamino)phenyl]ethanol |
NA |
153050 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
2,2,2-Trifluoro-1-[4-methoxy-2-(1,3-thiazol-4-ylmethylamino)phenyl]ethanol |
NA |
129690 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
4-Chloro-5-(dimethylsulfamoyl)-2-(furan-2-ylmethylamino)benzoic acid |
NA |
113130 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
2-chloro-4-(furan-2-ylmethylamino)-5-(hydroxymethyl)-N-methylbenzenesulfonamide |
NA |
117490 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
4-chloro-2-(furan-2-ylmethylamino)-N-methyl-5-(methylsulfamoyl)benzamide |
NA |
102590 |
NA |
NA |
NA |
NA |
BindingDB |
| APP |
4-Chloro-5-(cyclohexylsulfamoyl)-2-(furan-2-ylmethylamino)benzoic acid |
NA |
115520 |
NA |
NA |
NA |
NA |
BindingDB |