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Drugs And Genes
Negative Drug Target Genes
GENE_SYMBOL DRUG_NAME Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) Potency (nM) AC50 (nM) Datasource
F2 N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(toluene-4-sulfonylamino)-acetamide NA 357000 NA NA NA NA TTD
F2 4-Methoxybenzenecarboximidamide 1995262.31 NA NA NA NA NA TTD
F2 Benzamidine 258000|NA NA NA|355000|455000 NA NA NA ChEMBL
F2 3-[2-(4-Carbamimidoylbenzyloxy)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carbonylamino]propanoic acid 118000 NA NA NA NA NA TTD
F2 1-(4-chlorophenyl)-1H-tetrazole NA 330000 NA NA NA NA ChEMBL|TTD
F2 3-Amidinophenylpyruvic acid 100000000 NA NA NA NA NA TTD
F2 Bradykinin (1-5) NA 601000 NA NA NA NA TTD
F2 3,5-Dimethylbenzenecarboximidamide 10000000 NA NA NA NA NA TTD
F2 3-Phenylbenzenecarboximidamide 158489.32 NA NA NA NA NA TTD
F2 1-(4-Benzyloxy-benzyl)-piperidin-4-ylamine 581000 NA NA NA NA NA TTD
F2 3-(Aminoiminomethyl)benzoic acid 1995262.31 NA NA NA NA NA TTD
F2 [2-[(3,5-Dimethyl-1-phenylpyrazol-4-yl)amino]-2-oxoethyl] 2-(2-methylindol-1-yl)acetate NA 200000 NA NA NA NA TTD
F2 N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide 109000 NA NA NA NA NA TTD
F2 N-(4-Carbamimidoyl-3-choro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide 245000 NA NA NA NA NA TTD
F2 3-(Hydroxymethyl)benzene-1-carboximidamide 2511886.43 NA NA NA NA NA TTD
F2 {(S)-1-[2-(1-Formyl-4-guanidino-butylcarbamoyl)-ethylcarbamoyl]-4-guanidino-butyl}-carbamic acid tert-butyl ester NA 500000 NA NA NA NA TTD
F2 {(S)-1-[(S)-2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butyl}-carbamic acid tert-butyl ester NA 500000 NA NA NA NA TTD
F2 N-[3-(3-Amino-propoxy)-5-methyl-phenyl]-benzenesulfonamide 170000 NA NA NA NA NA TTD
F2 {[2-(1-Carbamimidoyl-piperidin-4-yl)-ethylcarbamoyl]-methyl}-carbamic acid 4-{[2-(1-carbamimidoyl-piperidin-4-yl)-ethylcarbamoyl]-methylcarbamoyloxymethyl}-benzyl ester 423000 NA NA NA NA NA TTD
F2 {[(1-Carbamimidoyl-piperidin-4-ylmethyl)-carbamoyl]-methyl}-carbamic acid 4-{[(1-carbamimidoyl-piperidin-4-ylmethyl)-carbamoyl]-methylcarbamoyloxymethyl}-benzyl ester 386000 NA NA NA NA NA TTD