| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SETD7 |
(3E,5E)-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(3-methylphenyl)methyl]piperidin-4-one |
NA |
667000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
(3E,5E)-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(4-methylphenyl)methyl]piperidin-4-one |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
(3E,5E)-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(2-chlorophenyl)methyl]piperidin-4-one |
NA |
667000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
(3E,5E)-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(4-chlorophenyl)methyl]piperidin-4-one |
NA |
600000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
(3E,5E)-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-(2-phenylethyl)piperidin-4-one |
NA |
667000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
(3E,5E)-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-(3-phenylpropyl)piperidin-4-one |
NA |
667000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide |
NA |
214000 |
NA |
NA |
NA |
NA |
TTD |
| SETD7 |
2-Hydroxy-1,4-naphthoquinone |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem |
| SETDB1 |
N-{[2-(3,5-Dimethyl-4h-1,2,4-Triazol-4-Yl)phenyl]methyl}acetamide |
NA |
NA |
3500000 |
NA |
NA |
NA |
ChEMBL |
| SETDB1 |
N-[[5-cyano-2-(3,5-dimethyl-1,2,4-triazol-4-yl)phenyl]methyl]acetamide |
NA |
NA |
1e+07 |
NA |
NA |
NA |
ChEMBL |
| SETDB1 |
N-[[2-(3,5-dimethyl-1,2,4-triazol-4-yl)phenyl]methyl]methanesulfonamide |
NA |
NA |
4e+06 |
NA |
NA |
NA |
ChEMBL |
| SETDB1 |
N-[[5-chloro-2-(3,5-dimethyl-1,2,4-triazol-4-yl)phenyl]methyl]acetamide |
NA |
NA |
2500000 |
NA |
NA |
NA |
ChEMBL |
| SETDB1 |
N-[[5-bromo-2-(3,5-dimethyl-1,2,4-triazol-4-yl)phenyl]methyl]acetamide |
NA |
NA |
2700000 |
NA |
NA |
NA |
ChEMBL |
| SETDB1 |
N-[[2-(3,5-dimethyl-1,2,4-triazol-4-yl)-5-methylphenyl]methyl]acetamide |
NA |
NA |
7700000 |
NA |
NA |
NA |
ChEMBL |
| SFRP1 |
nonasodium;(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-5-acetamido-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6S)-5-acetamido-4-hydroxy-6-pentoxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-2-carboxylato-4,5-dihydroxyoxan-3-yl]oxy-4-hydroxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfonatooxyoxane-2-carboxylate |
NA |
NA |
250000000 |
NA |
NA |
NA |
BindingDB |
| SFRP1 |
nonasodium;(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-5-acetamido-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-5-acetamido-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6S)-5-acetamido-4-hydroxy-6-pentoxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfonatooxyoxane-2-carboxylate |
NA |
NA |
250000000 |
NA |
NA |
NA |
BindingDB |
| SGK1 |
7-(4-fluoroanilino)-1-[(1R,3R)-3-hydroxycyclopentyl]-3-(4-methoxyphenyl)-4H-pyrimido[4,5-d]pyrimidin-2-one |
NA |
125000 |
NA |
NA |
NA |
NA |
TTD |
| SGK1 |
Kinase inhibitor, C2 |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB |
| SGK1 |
2-[4-(3-Phenylquinoxalin-2-yl)phenyl]propan-2-amine |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| SGK1 |
(+)-(1R,3R)-1-(3-hydroxy-cyclopentyl)-3-(4-methoxy-phenyl)-7-phenylamino-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one |
NA |
125000 |
NA |
NA |
NA |
NA |
TTD |