| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SGMS2 |
8-Tricyclo[5.2.1.02,6]decanyloxymethanedithioate |
NA |
224000 |
NA |
NA |
NA |
NA |
BindingDB |
| SGMS2 |
2-Anilino-2-(2-phenylmethoxyphenyl)acetamide |
NA |
135300 |
NA |
NA |
NA |
NA |
BindingDB |
| SHBG |
2,3-Bis(3'-hydroxybenzyl)butyrolactone |
NA |
620000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHBG |
7-Hydroxysecoisolariciresinol |
NA |
230000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHBG |
Secoisolariciresinol |
NA |
230000 |
NA |
NA |
NA |
NA |
PubChem |
| SHBG |
4-((1R,2R,5R,6R,9R)-5-Hydroxymethyl-6,8,9-trimethyl-3-oxa-bicyclo[3.3.1]non-7-en-2-yl)-phenol |
NA |
124500 |
NA |
NA |
NA |
NA |
BindingDB |
| SHC1 |
4-((S)-2-acetamido-3-((S)-5-amino-1-(2-((S)-1-amino-4-methyl-1-oxopentan-2-ylamino)-2-oxoethylamino)-1,5-dioxopentan-2-ylamino)-3-oxopropyl)phenyl dihydrogen phosphate |
NA |
248000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHC1 |
deamino-Orn(Ac)-Tyr(PO3H2)-Gln-Gly-Leu-Ser-NH2 |
NA |
NA |
158000 |
NA |
NA |
NA |
BindingDB |
| SHC1 |
[4-[(2S)-2-acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-enylamino)propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
189000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHC1 |
[4-[(2S)-2-acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-1-(but-3-enylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
165000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHC1 |
[4-[(2S)-2-acetamido-3-[[(2S)-5-amino-1-[[2-[[(2S)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-enylamino)propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-prop-2-enylamino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
353000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHC1 |
[4-[(2S)-2-[acetyl(prop-2-enyl)amino]-3-[[(2S)-5-amino-1-[[2-[[(2S)-4-methyl-1-oxo-1-(prop-2-enylamino)pentan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
450000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHH |
nonasodium;(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6S)-6-(5-aminopentoxy)-4-hydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy-2-carboxylato-4-hydroxy-5-sulfonatooxyoxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfonatooxyoxane-2-carboxylate |
NA |
NA |
122000 |
NA |
NA |
NA |
BindingDB |
| SHMT1 |
2-[[2-[2-[4-Chloro-2-(2-hydroxyethyl)phenyl]-1,3-thiazol-4-yl]acetyl]amino]acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHMT1 |
2-[[2-[2-[2-(2-Amino-2-oxoethyl)-4-chlorophenyl]-1,3-thiazol-4-yl]acetyl]amino]acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHMT1 |
2-[[2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-4-yl]acetyl]amino]acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHMT1 |
2-[[2-[2-(2,4-Dichlorophenyl)-1,3-thiazol-4-yl]-2-methylpropanoyl]amino]acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHMT1 |
Pemetrexed |
185600 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| SHMT1 |
2-[[2-[2-(2,4-Dichlorophenyl)-1,3-thiazol-4-yl]-2-phenylacetyl]amino]acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |
| SHMT1 |
(2S)-2-[[2-[2-(2,4-dichlorophenyl)-1,3-thiazol-4-yl]acetyl]amino]-4-methylpentanoic acid;sulfane |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |