| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SI |
(2S,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol |
NA |
450000 |
NA |
NA |
NA |
NA |
BindingDB |
| SI |
L-ido Miglustat |
NA |
1000000 |
NA |
NA |
NA |
NA |
BindingDB |
| SI |
1-Deoxynojirimycin |
NA |
192000 |
NA |
NA |
NA |
NA |
PubChem |
| SI |
Glucobay |
NA |
817000|320000|101500|817380|707900|576200|942000|442400|452243|200800|1520000|583600 |
NA |
NA |
NA |
NA |
PubChem |
| SI |
Gypsophin |
NA |
305000 |
NA |
NA |
NA |
NA |
BindingDB |
| SI |
N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-altro-1-deoxynojirimycin |
NA |
1000000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIGMAR1 |
5-(1,2-Dithiolan-3-YL)-1-(4-phenylpiperazin-1-YL)pentan-1-one |
1700000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
[(6aR,10aR)-7-methyl-4-propan-2-yl-6,6a,8,10a-tetrahydroindolo[4,3-fg]quinolin-9-yl]methyl 4-methoxycyclohexane-1-carboxylate |
NA |
157000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT1 |
(4-Bromophenyl)(5-methoxy-2-methylnaphtho[1,2-b]furan-3-yl)methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
1-(6-Chloro-2,2-dimethyl-3,4-dihydrochromen-4-yl)-3-(4-nitrophenyl)thiourea |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(4,6-Dibromo-5-hydroxy-1-benzofuran-3-yl)-phenylmethanone |
NA |
198000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
(4,6-Dibromo-5-hydroxy-1-benzofuran-3-yl)(2,5-dimethoxyphenyl)methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(4-Bromophenyl)(5-hydroxynaphtho[1,2-b]furan-3-yl)methanone |
NA |
146000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
3-[(2-Methoxynaphthalen-1-yl)methyl]-7-[(4-methoxyphenyl)methylamino]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one |
NA |
119400 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
3-[[(5S)-6-anilino-6-oxo-5-(phenylmethoxycarbonylamino)hexyl]amino]-3-sulfanylidenepropanoic acid |
NA |
256000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT1 |
(2S)-6-acetamido-2-[[(2S)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-(propan-2-ylcarbamothioylamino)hexanoyl]amino]hexanamide |
NA |
117900 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
2-({[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]carbonyl}amino)-5-hydroxybenzoic acid |
NA |
424000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
5-[[3-[(4-Phenylmethoxybenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
5-[(3-Acetamidophenyl)methoxy]pyridine-3-carboxamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
N-[3-[(5-carbamoylpyridin-3-yl)oxymethyl]phenyl]-6-thiophen-2-ylpyridine-3-carboxamide |
NA |
145000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |