| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SIRT1 |
2-(3-Benzyloxyphenylamino)Benzamide |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
2-[3-(3-Phenylpropoxy)anilino]benzamide |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(2,5-Dimethoxyphenyl)(5-hydroxy-1-benzofuran-3-yl)methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(2,5-Dimethoxy-phenyl)-(5-hydroxy-4-morpholin-4-ylmethyl-benzofuran-3-yl)-methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
4-[4-(Furan-2-amido)benzamido]-2-hydroxybenzoic acid |
NA |
599000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid |
NA |
1578000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
[5-Hydroxy-4-(4-morpholinylmethyl)-1-benzofuran-3-yl](phenyl)methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(s)-8-Bromo-6-chloro-2-pentylchroman-4-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
3-(2-Furyl)-6-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole |
NA |
132800 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT1 |
2-methyl-8-(4-methylsulfonylphenyl)-5-octyl-3,4-dihydro-1H-pyrido[4,3-b]indole |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
tert-butyl N-[4-[(4-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate |
NA |
121200 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
tert-butyl N-[2,2-dimethyl-4-[(3-nitrophenyl)carbamoylamino]-3,4-dihydrochromen-6-yl]carbamate |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
4-tert-Butylbenzoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
(5-Hydroxynaphtho[1,2-b]furan-3-yl)(4-methoxyphenyl)methanone |
NA |
256000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
(5-Hydroxynaphtho[1,2-b]furan-3-yl)(phenyl)methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(5-Hydroxynaphtho[1,2-b]furan-3-yl)(4-methylphenyl)methanone |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
3-(2,5-Dimethoxybenzoyl)-1-benzofuran-5-yl acetate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(4-Bromophenyl)(5-hydroxy-2-methyl-1-benzofuran-3-yl)methanone |
NA |
243000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT1 |
3-Benzoyl-1-benzofuran-5-yl acetate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT1 |
(4-Bromophenyl)(5-hydroxy-1-benzofuran-3-yl)methanone |
NA |
240000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |