| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SIRT2 |
H-Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Met-OH |
NA |
124000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT2 |
H-Asp-D-Trp-Phe-D-Trp-Gly-Leu-Met-OH |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT2 |
H-Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Gly-OH |
NA |
126000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT2 |
benzyl 2-[(2R)-3-bis(phenylmethoxy)phosphoryloxy-2-(oxolan-2-yloxy)propyl]sulfinylacetate |
NA |
289000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT2 |
Resveratrol |
NA |
NA |
NA |
300000 |
NA |
NA |
PubChem|TTD |
| SIRT2 |
(E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-fluorophenyl)acrylamide |
NA |
105000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
Asp-Lys(epsilon-thioAc)-Thr |
NA |
175000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
Lys-Lys(epsilon-thioAc)-Leu |
NA |
151000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
Ser-Asp-Lys(epsilon-thioAc)Leu-Ile |
NA |
238000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
(Z)-6,7-Dichloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]indolin-2-one |
NA |
135400 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
10-Phenyl-7-oxa-8,10-diaza-benzo[a]anthracene-9,11-dione |
NA |
191200 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT2 |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-pivalamidohexanamido)propanoate |
NA |
338000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
N-[(3-pyridin-3-yl-1H-1,2,4-triazol-5-yl)methyl]pyrazine-2-carboxamide |
NA |
2290000 |
NA |
NA |
NA |
NA |
BindingDB |
| SIRT2 |
N-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide |
NA |
159000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
2,4-dioxo-N-(4-(pyridin-3-yloxy)phenyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide |
NA |
114000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
1,2-Dihydro-3H-naphtho(2,1-b)pyran-3-one |
NA |
112900 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-(cyclohex-1-enecarboxamido)hexanamido)propanoate |
NA |
129000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
(S)-2-((S)-6-Acetamido-2-((S)-2-acetamidopropanamido)hexanamido)propanoic acid |
NA |
223000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
(S)-Methyl 2-((S)-6-acetamido-2-((S)-2-acetamidopropanamido)hexanamido)propanoate |
NA |
180000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SIRT2 |
Sunitinib |
NA |
122700 |
NA |
NA |
NA |
NA |
BindingDB|PubChem|TTD |