| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SIRT5 |
(2S,5S,8S)-5-[4-(ethanethioylamino)butyl]-2-(naphthalen-2-ylmethyl)-3,6,12,19-tetraoxo-1,4,7,11-tetrazacyclononadecane-8-carboxamide |
NA |
6000000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S,5S,8S)-2-(1-benzothiophen-3-ylmethyl)-5-[4-(ethanethioylamino)butyl]-3,6,12,19-tetraoxo-1,4,7,11-tetrazacyclononadecane-8-carboxamide |
NA |
2000000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S,5S,8S)-2-(1-benzothiophen-3-ylmethyl)-5-[4-(ethanethioylamino)butyl]-3,6,13,20-tetraoxo-1,4,7,12-tetrazacycloicosane-8-carboxamide |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S)-4-anilino-2-naphthalen-2-ylsulfanyl-4-oxobutanoic acid |
NA |
157200 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S)-4-(benzylamino)-2-naphthalen-2-ylsulfanyl-4-oxobutanoic acid |
NA |
124000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S)-4-(butylamino)-2-naphthalen-2-ylsulfanyl-4-oxobutanoic acid |
NA |
154000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S)-6-amino-2-[[2-[[2-[[(2S,3R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-[4-(decylamino)-4-oxobutyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(2S)-6-amino-2-[[2-[[2-[[(2S,3R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-[4-(octylamino)-4-oxobutyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(3S,6S,23S)-6-[3-(diaminomethylideneamino)propyl]-3-[6-(dodecylamino)-6-oxohexyl]-2,5,8,11,14,17-hexaoxo-1,4,7,10,15,18-hexazacyclotricosane-23-carboxamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
(3S,6S,23S)-6-[3-(diaminomethylideneamino)propyl]-3-[4-(dodecylcarbamothioylamino)butyl]-2,5,8,11,14,17-hexaoxo-1,4,7,10,15,18-hexazacyclotricosane-23-carboxamide |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| SIRT5 |
Anthralin |
NA |
453400 |
NA |
NA |
NA |
NA |
PubChem |
| SIRT5 |
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem |
| SIRT6 |
Myristic Acid |
NA |
NA |
NA |
246000 |
NA |
NA |
BindingDB|PubChem |
| SIRT6 |
Trichostatin A |
NA|450000 |
NA |
445000|NA|227000 |
NA |
NA |
NA |
PubChem |
| SIRT6 |
(3R,5S)-Fluvastatin |
NA |
NA |
NA |
250000 |
NA |
NA |
PubChem |
| SIRT6 |
Quercetin |
NA |
NA |
NA |
990000 |
NA |
NA |
PubChem |
| SIRT6 |
Luteolin |
NA |
NA |
NA |
270000 |
NA |
NA |
PubChem |
| SIRT6 |
Linoleic Acid |
NA |
NA |
NA |
230000 |
NA |
NA |
PubChem |
| SIRT6 |
Delphinidin |
NA |
NA |
NA |
760000 |
NA |
NA |
PubChem |
| SIRT6 |
Cyanidin chloride |
NA |
NA |
NA |
460000 |
NA |
NA |
BindingDB |