| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ST14 |
H-Cys(1)-Pro-Ala-Tyr-Ser-Arg-Tyr-Leu-Asp-Cys(1)-OH |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-amino-29-(4-aminobutyl)-11,23-dibenzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17-methyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-amino-11,23-dibenzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-amino-23-benzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-amino-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-11-(carboxymethyl)-23-(hydroxymethyl)-17,26-bis[(4-hydroxyphenyl)methyl]-29-methyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
cyclo[Arg-Cys(1)-Tyr-Lys-Ser-Ile-Pro-Pro-Ile-Cys(1)-Phe-Pro-Asp-Gly] |
480000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ST14 |
(Z)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)-N-(4-methoxyphenyl)prop-2-enamide |
NA |
120000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ST14 |
(5E)-5-[(3,4-Dimethoxyphenyl)methylidene]-3-{[(5-fluoro-2-methylphenyl)amino]methyl}-1,3-thiazolidine-2,4-dione |
NA |
103000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ST14 |
Benzamidine |
400000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ST14 |
cyclo[Arg-Ser-Thr-Lys-Ser-Ile-Pro-Pro-Ile-Ser-Phe-Pro-Asp-Gly] |
107000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ST14 |
cyclo[Arg-Cys(1)-Thr-Orn-Ser-Ile-Pro-Pro-Ile-Cys(1)-Phe-D-Pro-Asp-Gly] |
250000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
cyclo[Arg-Ser-Thr-Lys-Ser-Ile-Pro-Pro-Ile-Ser-Phe-D-Pro-Asp-Gly] |
107000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
3-Amino-N-(3-{(S)-1-[4-(2-amino-ethyl)-piperidine-1-carbonyl]-3-phenyl-propylsulfamoyl}-phenyl)-propionamide |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
3-Amino-N-(3-{(S)-1-[4-(2-amino-ethyl)-piperidine-1-carbonyl]-4-phenyl-butylsulfamoyl}-phenyl)-propionamide |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ST14 |
(E)-3-[3-[(4-chlorophenoxy)methyl]-4-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
NA |
138000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ST14 |
(Z)-2-(1H-benzimidazol-2-yl)-3-[3-methoxy-4-(2-morpholin-4-yl-2-oxoethoxy)phenyl]prop-2-enenitrile |
NA |
128000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ST14 |
(Z)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenyl)prop-2-enamide |
NA |
111000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STAT1 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-1-[(3-methoxyphenyl)carbamoyl]-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
560000 |
NA |
NA |
NA |
NA |
TTD |
| STAT1 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-1-[(3-hydroxypropyl)carbamoyl]-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
620000|210000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STAT1 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-1-(cyclohexylcarbamoyl)-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
605000 |
NA |
NA |
NA |
NA |
TTD |