| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| STAT1 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-(phenylcarbamoyl)butyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
310000|380000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STAT1 |
4-[(2S)-2-{[(1S)-1-(benzylcarbamoyl)-3-methylbutyl]carbamoyl}-2-[(4-cyanophenyl)formamido]ethyl]phenoxyphosphonic acid |
NA |
800000|760000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STAT1 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-[(2-methylpropyl)carbamoyl]butyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| STAT1 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-[(pyridin-4-ylmethyl)carbamoyl]butyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
123000|402000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STAT1 |
4-((4-(Hexylcarbamoyl)-2-(naphthalen-1-yl)oxazol-5-yl)methyl)phenyl dihydrogen phosphate |
NA |
159000 |
NA |
NA |
NA |
NA |
BindingDB |
| STAT1 |
STAT5 Inhibitor |
NA |
130000 |
NA |
NA |
NA |
NA |
TTD |
| STAT1 |
(2S)-2-[(2S)-2-[(4-cyanophenyl)formamido]-3-[4-(phosphonooxy)phenyl]propanamido]-4-methylpentanoic acid |
NA |
310000 |
NA |
NA |
NA |
NA |
BindingDB |
| STAT3 |
4-[[2-[(4-Chlorophenyl)methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-[(3,5-ditert-butylphenyl)methyl]amino]-2-hydroxybenzoic acid |
143800 |
NA |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
Phaeosphaeride A |
NA |
610000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
3-({2-chloro-4-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]-6-ethoxyphenoxy}methyl)benzoic acid |
NA |
144000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
(3S)-3-[({[(1S)-2-carbamoyl-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}ethyl]carbamoyl}methyl)carbamoyl]-3-[(2S)-2-[(2S)-2-acetamido-3-[4-(phosphonooxy)phenyl]propanamido]-3-hydroxypropanamido]propanoic acid |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-1-[(3-hydroxypropyl)carbamoyl]-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
620000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-(phenylcarbamoyl)butyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
310000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
4-[(2S)-2-{[(1S)-1-(benzylcarbamoyl)-3-methylbutyl]carbamoyl}-2-[(4-cyanophenyl)formamido]ethyl]phenoxyphosphonic acid |
NA |
800000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
4-[(2S)-2-[(4-cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-[(pyridin-4-ylmethyl)carbamoyl]butyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
123000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
2-Hydroxy-4-[[2-[(4-methylphenyl)sulfonylamino]acetyl]amino]benzoic acid |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
Ac-Tyr(PO3H2)-His-Asn-Gln-D-Pro-Leu-NH2 |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
(S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-acetamido-3-(4-(phosphonomethyl)phenyl)propanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamido)-5-amino-5-oxopentanamido)-3-hydroxybutanamido)-3-methylbutanoic acid |
NA |
138000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
2-(benzo[d][1,3]dioxol-5-yl)-N-(3,4-dihydroxyphenethyl)acetamide |
NA |
357000 |
NA |
NA |
NA |
NA |
TTD |
| STAT3 |
[(2R,3S,4S,5R,6S)-3,5-dihydroxy-2-methyl-6-[(2S)-6-methyl-2-[(1S)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-yl]oxyoxan-4-yl] 3-methylbut-2-enoate |
NA |
110000 |
NA |
NA |
NA |
NA |
TTD |