| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDO2 |
5-aminooxy-5-(3-chlorophenyl)-N-phenylpentanamide;hydrochloride |
NA |
123000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TDO2 |
2-fluoro-N-hydroxy-N'-(4-nitro-2,1,3-benzoxadiazol-7-yl)benzenecarboximidamide |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
2-[6-(1H-indol-3-yl)benzotriazol-1-yl]acetic acid |
NA |
104500 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
2-[5-(1H-indol-3-yl)benzotriazol-1-yl]acetic acid |
NA |
173800 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
4-[2-[5-(1H-indol-3-yl)benzotriazol-1-yl]ethyl]morpholine |
NA |
118600 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
5-(1H-indol-3-yl)-1-(oxolan-2-ylmethyl)benzotriazole |
NA |
253000 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
2-[(6-bromo-1H-indazol-4-yl)amino]-1-(4-hydroxyphenyl)ethanone |
NA |
147700 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
Pf-06840003 |
NA |
140000|378000 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| TDO2 |
9-Chloroindolo[2,1-b]quinazoline-6,12-dione |
NA |
224200 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
Ac-Asp-Phe-Asp-Asp-Leu-Asn-Phe-Thr-Gly-Met-Pro-Pro-Ala-Asp-Glu-Asp-Tyr-Ser-Pro-NH2 |
NA |
157600 |
NA |
NA |
NA |
NA |
BindingDB |
| TDO2 |
Tryptophan |
11500000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem|TTD |
| TDP1 |
6-(3-Hydroxypropyl)-5H-indeno[1,2-c]isoquinoline-5,11(6H)-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(5-Hydroxypentyl)indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5,6-Dihydro-6-(4-hydroxy-1-butyl)-5,11-diketo-11H-indeno[1,2-c]isoquinoline |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-Hydroxy-8-methoxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-Hydroxy-6-(3-imidazol-1-ylpropyl)-8-methoxy-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
8-Hydroxy-9-methoxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
7-Hydroxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
7-Hydroxy-6-(3-imidazol-1-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
8-Hydroxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |