| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
8-Hydroxy-6-(3-imidazol-1-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-Hydroxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione;hydrobromide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-Hydroxy-6-(3-imidazol-1-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione;hydrochloride |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
10-Hydroxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
10-Hydroxy-6-(3-imidazol-1-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione;hydrobromide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[(2S)-2,3-dihydroxypropyl]-3-iodoindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Morpholin-4-ylpropyl)indeno[1,2-c][2,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Imidazol-1-ylpropyl)indeno[1,2-c][2,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(furan-2-yl)-4H-isoquinoline-1,3-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(Z)-5-(4-Fluorobenzylidene)-1,3-thiazolidine-2,4-dione |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[(2S)-2,3-dihydroxypropyl]indeno[1,2-c][2,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Morpholin-4-ylpropyl)indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Morpholin-4-ylpropyl)indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Imidazol-1-ylpropyl)indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[(2S)-2,3-dihydroxypropyl]indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[(2S)-2,3-dihydroxypropyl]indeno[1,2-c][2,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Imidazol-1-ylpropyl)indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[3-(Dimethylamino)propyl]indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[(2S)-2,3-dihydroxypropyl]indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Morpholin-4-ylpropyl)indeno[1,2-c][2,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |