| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
Paromomycin |
NA |
21000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TDP1 |
Tyrphostin A25 |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
n,n'-Bis(phenylacetyl)cystine |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(5Z)-5-[(3,4-dihydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Camptothecin |
NA |
111000 |
NA |
NA |
NA |
NA |
PubChem |
| TDP1 |
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol |
NA |
8000000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(2-Hydroxyethyl)-5H-indeno[1,2-c]isoquinoline-5,11(6H)-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Puromycin |
NA |
18000000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Netilmicin |
NA |
8000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TDP1 |
Clindamycin Phosphate |
NA |
9100000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TDP1 |
N-[3-[(3-amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(1R,8S,11Z,18S,25S,26R,37S,40S,46S,53S,59S)-37-[(2S)-butan-2-yl]-18-[(2S,3R)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[(1R)-1-hydroxyethyl]-31-[(1S)-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide |
NA |
1800000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TDP1 |
Tyrphostin A46 |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
AG 490 |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(5Z)-5-[(4-fluorophenyl)methylidene]-3-phenyl-2-sulfanylideneimidazolidin-4-one |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(4Z)-4-[[4-[bis(2-cyanoethyl)amino]phenyl]methylidene]-5-oxo-1-(4-sulfophenyl)pyrazole-3-carboxylic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(furan-2-yl)-2-hydroxy-4H-isoquinoline-1,3-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[10-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)decyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[11-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)undecyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[12-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)dodecyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |