| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
6-(3-Imidazol-1-ylpropyl)indeno[1,2-c][2,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
4-hydroxy-5-[(E)-indol-5-ylidenemethyl]-3H-1,3-thiazol-2-one |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(5E)-5-(1H-indol-5-ylmethylene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(5Z)-5-[(2,3-dihydroxyphenyl)methylidene]-4-sulfanylidene-1,3-thiazolidin-2-one |
NA |
220000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
3-benzyl-5-hydroxy-4-[(E)-indol-5-ylidenemethyl]-1H-imidazole-2-thione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
4-sulfanyl-5-[(E)-[6-(tetrazol-5-ylidene)cyclohexa-2,4-dien-1-ylidene]methyl]-3H-1,3-thiazol-2-one |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-14-methoxy-9-[3-(4-methylpiperazin-1-yl)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-[3-(4,5-Dihydro-1,3-thiazol-2-ylamino)propyl]-5-fluoro-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-14-methoxy-9-(3-piperazin-1-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-14-methoxy-9-(3-morpholin-4-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-14-methoxy-9-[3-(methylamino)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl]-14-methoxy-5-nitro-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-14-methoxy-9-[3-(propan-2-ylamino)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-[3-(Ethylamino)propyl]-5-fluoro-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-9-(3-imidazol-1-ylpropyl)-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-14-methoxy-9-(3-pyrrolidin-1-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Chloro-9-(3-imidazol-1-ylpropyl)-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Fluoro-9-[3-(4-hydroxypiperidin-1-yl)propyl]-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-Chloro-14-methoxy-9-(3-morpholin-4-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-Propenethioamide, 3-(4-bromophenyl)-2-cyano-, (E)- |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |