| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
4-bromo-N-[12-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)dodecyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[3-(3-nitro-5,11-dioxo-9-phenylindeno[1,2-c]isoquinolin-6-yl)propyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[3-(11,20-dioxo-5,7-dioxa-12-azapentacyclo[11.7.0.02,10.04,8.014,19]icosa-1(13),2,4(8),9,14,16,18-heptaen-12-yl)propyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 6-[3-(benzenesulfonamido)propyl]-2,3-dimethoxy-5,11-dioxoindeno[1,2-c]isoquinoline-9-carboxylate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[3-(3-nitro-5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[3-(2,3-dimethoxy-5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propyl]benzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[10-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)decyl]indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[11-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)undecyl]indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[12-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)dodecyl]indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(6-Hydroxyhexyl)indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(7-Hydroxyheptyl)indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
4-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)butyl 4-methylbenzenesulfonate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)pentyl 4-methylbenzenesulfonate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)hexyl 4-methylbenzenesulfonate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
7-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)heptyl 4-methylbenzenesulfonate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[2-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)ethyl]methanesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[3-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propyl]methanesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[4-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)butyl]methanesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[5-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)pentyl]methanesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[6-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)hexyl]methanesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |