| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
N-[4-[(E)-3-amino-2-cyano-3-sulfanylideneprop-1-enyl]phenyl]acetamide |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N-[6-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)hexyl]-3-methylbenzenesulfonamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
3-(5,11-Dioxoindeno[1,2-c]isoquinolin-6-yl)propyl 4-methylbenzenesulfonate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
4-[(Z)-(5-oxo-1-phenyl-2-sulfanylideneimidazolidin-4-ylidene)methyl]benzoic acid |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-[(Z)-(2-oxo-4-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzoic acid |
NA |
138000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
4-[(Z)-(3-benzyl-5-oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]benzoic acid |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-Hydroxy-2,3,8-trimethoxy-6-(3-morpholin-4-ylpropyl)indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(E)-2-cyano-3-(1H-indol-5-yl)prop-2-enethioamide |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
8-Hydroxy-6-(3-imidazol-1-ylpropyl)-2,3,9-trimethoxyindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(5Z)-1-benzyl-5-[(4-fluorophenyl)methylidene]-2-sulfanylideneimidazolidin-4-one |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
9-Hydroxy-6-(3-imidazol-1-ylpropyl)-2,3,8-trimethoxyindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
8-Methoxy-6-(3-morpholin-4-ylpropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Imidazol-1-ylpropyl)-5,11-dioxoindeno[1,2-c]isoquinoline-3-carbonitrile |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Morpholin-4-ylpropyl)-5,11-dioxoindeno[1,2-c]isoquinoline-3-carbonitrile |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
20-[3-(Dimethylamino)propyl]-11,19-dioxo-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13(18),14,16-heptaene-16-carbonitrile |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 2-[(6-Methyl-5,11-dioxo-6,11-dihydro-5H-indeno[1,2-c]isoquinolin-3-yl)amino]-2-oxoacetate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 3-[(6-Methyl-5,11-dioxo-6,11-dihydro-5H-indeno[1,2-c]isoquinolin-3-yl)amino]-3-oxopropanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 4-[(6-methyl-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl)amino]-4-oxobutanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 5-[(6-methyl-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl)amino]-5-oxopentanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 6-[(6-methyl-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl)amino]-6-oxohexanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |