| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
3-[(6-Methyl-5,11-dioxo-6,11-dihydro-5H-indeno[1,2-c]isoquinolin-3-yl)amino]-3-oxopropanoic Acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 3-[[6-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-3-oxopropanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 4-[[6-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-4-oxobutanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 5-[[6-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-5-oxopentanoate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-[[6-[3-[(2-Methylpropan-2-yl)oxycarbonylamino]propyl]-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-5-oxopentanoic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-[[6-(3-Aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-2-oxoacetic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
3-[[6-(3-Aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-3-oxopropanoic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
4-[[6-(3-Aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-4-oxobutanoic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
5-[[6-(3-Aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-5-oxopentanoic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[[6-(3-Aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-6-oxohexanoic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Ethyl 2-[(6-methyl-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl)amino]acetate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-[(6-Methyl-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl)amino]acetic acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-((6-(3-((tert-Butoxycarbonyl)amino)propyl)-5,11-dioxo-6,11-dihydro-5H-indeno[1,2-c]isoquinolin-3-yl)amino)acetic Acid |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Bromopropyl)-5,6-dihydro-8-methoxy-3-nitro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(3-Azidopropyl)-8-methoxy-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Lividomycin A |
NA |
30000000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
(E)-2-cyano-3-(4-nitrophenyl)prop-2-enethioamide |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
20-[(2S)-2,3-dihydroxypropyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-(2,3-Dihydroxypropyl)-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
15,16-dimethoxy-20-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |