| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP1 |
15,16-dimethoxy-20-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
15,16-dimethoxy-20-[(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
3-nitro-6-[(2S,3R,4S,5R)-2,3,4,5,6-pentahydroxyhexyl]indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
15,16-dimethoxy-20-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
6-[(2R)-2,3-dihydroxypropyl]-3-nitroindeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
15,16-dimethoxy-20-[(2S,3R,4R)-2,3,4,5-tetrahydroxypentyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
3-nitro-6-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]indeno[1,2-c]isoquinoline-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
20-(2,3-Dihydroxypropyl)-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
20-[(2R)-2,3-dihydroxypropyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-Cyano-3-(4-fluorophenyl)-2-propenethioamide |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Framycetin |
NA |
8000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TDP1 |
16-Methoxy-15-(3-morpholin-4-ylpropoxy)-20-(3-morpholin-4-ylpropyl)-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
Methyl 2-[[16-methoxy-20-(3-morpholin-4-ylpropyl)-11,19-dioxo-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-15-yl]oxy]acetate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
2-[[11-Hydroxy-16-methoxy-20-(3-morpholin-4-ylpropyl)-19-oxo-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-15-yl]oxy]acetohydrazide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
16-Methoxy-15-[3-(4-methylpiperazin-1-yl)propoxy]-20-(3-morpholin-4-ylpropyl)-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
16-Methoxy-20-(3-morpholin-4-ylpropyl)-15-prop-2-enoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP1 |
N,N'-Dibenzoylcystine |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
{4-bromo-2-[(Z)-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]phenoxy}acetic acid |
NA |
128316 |
NA |
NA |
NA |
NA |
BindingDB |
| TDP2 |
7-(Morpholin-4-yl)-2,1,3-benzoxadiazol-4-amine |
NA |
128345 |
NA |
NA |
NA |
NA |
BindingDB |
| TDP2 |
10-(2,5-Dimethyl-phenyl)-7-nitro-10H-pyrimido[4,5-b]quinoline-2,4-dione |
NA |
128332 |
NA |
NA |
NA |
NA |
BindingDB |