| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP2 |
3-amino-2-pyridin-3-yl-7H-pyrazolo[4,3-c]pyridine-4,6-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-[(2S)-2,3-dihydroxypropyl]indeno[1,2-c][2,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Morpholin-4-ylpropyl)indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Morpholin-4-ylpropyl)indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Imidazol-1-ylpropyl)indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-[3-(Dimethylamino)propyl]indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-[(2S)-2,3-dihydroxypropyl]indeno[1,2-h][1,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Aminopropyl)indeno[1,2-c][2,6]naphthyridine-5,11-dione;dihydrochloride |
NA |
111000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TDP2 |
6-[(2S)-2,3-dihydroxypropyl]indeno[1,2-c][2,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TDP2 |
6-(3-Aminopropyl)indeno[1,2-c][2,7]naphthyridine-5,11-dione;dihydrochloride |
NA |
111000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TDP2 |
6-(3-Imidazol-1-ylpropyl)indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-[3-(Dimethylamino)propyl]indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-[(2S)-2,3-dihydroxypropyl]indeno[2,1-f][1,7]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Aminopropyl)indeno[2,1-f][1,7]naphthyridine-5,11-dione;dihydrochloride |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Aminopropyl)indeno[1,2-h][1,6]naphthyridine-5,11-dione;dihydrochloride |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Morpholin-4-ylpropyl)indeno[1,2-c][2,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
6-(3-Imidazol-1-ylpropyl)indeno[1,2-c][2,6]naphthyridine-5,11-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile |
NA |
128332 |
NA |
NA |
NA |
NA |
BindingDB |
| TDP2 |
5-Fluoro-14-methoxy-9-[3-(4-methylpiperazin-1-yl)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Fluoro-14-methoxy-9-(3-piperazin-1-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
107000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |