| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TDP2 |
5-Chloro-14-methoxy-9-[3-(propan-2-ylamino)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-14-methoxy-9-(3-pyrrolidin-1-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Fluoro-14-methoxy-9-(3-morpholin-4-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Fluoro-14-methoxy-9-[3-(methylamino)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
108000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TDP2 |
9-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl]-14-methoxy-5-nitro-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-14-methoxy-9-(3-piperazin-1-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-9-[3-(4-hydroxypiperidin-1-yl)propyl]-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Fluoro-14-methoxy-9-[3-(propan-2-ylamino)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-14-methoxy-9-[3-(methylamino)propyl]-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-9-[3-(ethylamino)propyl]-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
9-[3-(Ethylamino)propyl]-5-fluoro-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
104000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TDP2 |
5-Fluoro-9-(3-imidazol-1-ylpropyl)-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Fluoro-14-methoxy-9-(3-pyrrolidin-1-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-9-(3-imidazol-1-ylpropyl)-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Fluoro-9-[3-(4-hydroxypiperidin-1-yl)propyl]-14-methoxy-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
5-Chloro-14-methoxy-9-(3-morpholin-4-ylpropyl)-9,12-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-8,17-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
3-(1,3-Benzoxazol-2-yl)-2-methylfuro[2,3-g]quinoline-4,9-dione |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
ethyl 2-methyl-4,9-dioxo-1H-pyrrolo[3,2-g]quinoline-3-carboxylate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
N-(3-chlorophenyl)-2-methyl-4,9-dioxofuro[3,2-g]quinoline-3-carboxamide |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |
| TDP2 |
ethyl 4,9-dioxo-2H-pyrazolo[4,3-g]quinoline-3-carboxylate |
NA |
111000 |
NA |
NA |
NA |
NA |
TTD |