| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TERF2 |
(3S,6S,9S,16S,19S)-9-[[(2S)-2-amino-3-phenylpropanoyl]amino]-N,N,3-trimethyl-6-(2-methylpropyl)-2,5,8,18-tetraoxo-1,4,7,17-tetrazabicyclo[17.3.0]docosane-16-carboxamide |
130300 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TERF2 |
H-Lys-Tyr-Leu-Leu-Thr-Pro-Val-OH |
122600 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TERF2 |
H-Leu-Leu-Thr-Pro-Val-NH2 |
500000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TERT |
N-[9-Oxo-7-(3-piperidin-1-yl-propionylamino)-9H-fluoren-2-yl]-3-piperidin-1-yl-propionamide |
NA |
8912509381 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
3-[(3,8-Diamino-5-ethyl-6-phenylphenanthridin-5-ium-7-yl)diazenyl]benzenecarboximidamide |
NA |
97723722|97723722.1 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TERT |
Quinolinium, 6,6'-[(6-amino-1,3,5-triazine-2,4-diyl)diimino]bis[1-methyl- |
NA |
128824955 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
2-piperidin-1-yl-N-(quinolino[3,2-a]acridin-6-ylmethyl)ethanamine |
NA |
1995262315 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
3,6-Bis[3-(Azepan-1-Yl)propionamido]acridine |
NA |
3090295433 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
N-[[10-[[3-(dimethylamino)propylamino]methyl]quinolino[2,3-a]acridin-2-yl]methyl]-N',N'-dimethylpropane-1,3-diamine |
NA |
28183829 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
N-[[3-(propylaminomethyl)quinolino[3,2-c]acridin-10-yl]methyl]propan-1-amine |
NA |
501187234 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
Altertoxin I |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TERT |
N',N'-dimethyl-N-(16-nitro-4,12-diazapentacyclo[11.8.0.02,11.05,10.014,19]henicosa-1(13),2(11),3,5,7,9,14(19),15,17,20-decaen-3-yl)propane-1,3-diamine |
NA |
501187234 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
1N-{7-[2-(2-hydroxymethyl-1-methylhexahydro-1-pyridiniumyl)ethylcarboxamido]-9-oxo-9H-2-fluorenyl}-3-(2-hydroxymethyl-1-methylhexahydro-1-pyridiniumyl)propanamide; diiodide |
NA |
33113112148 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
3-diethyl-3-methylammonium-N-[7-(3-diethyl-3-methylammonium-propionylamino)-9-oxo-9H-fluoren-2-yl]-propionamide; diiodide |
NA |
25118864315 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
1N-{7-[2-(4-methyl-1,4-oxazinan-4-ium-4-yl)ethylcarboxamido]-9-oxo-9H-2-fluorenyl}-3-(4-methyl-1,4-oxazinan-4-ium-4-yl)propanamide; diiodide |
NA |
27542287033 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
3-trimethylammonium-N-[7-(3-trimethylammonium-propionylamino)-9-oxo-9H-fluoren-2-yl]-propionamide; diiodide; Hydrate |
NA |
18620871367 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
1N-{7-[2-(1-methylhexahydro-1-pyridiniumyl)ethylcarboxamido]-9-oxo-9H-2-fluorenyl}-3-(1-methylhexahydro-1-pyridiniumyl)propanamide; diiodide |
NA |
20892961309 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
N-[[2-(propylaminomethyl)quinolino[3,2-a]acridin-11-yl]methyl]propan-1-amine |
NA |
1000000000 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
3-[2-(2-Hydroxy-ethyl)-piperidin-1-yl]-N-(7-{3-[2-(2-hydroxy-ethyl)-piperidin-1-yl]-propionylamino}-9-oxo-9H-fluoren-2-yl)-propionamide |
NA |
16595869074 |
NA |
NA |
NA |
NA |
BindingDB |
| TERT |
N-[[3-[[3-(dimethylamino)propylamino]methyl]quinolino[3,2-c]acridin-10-yl]methyl]-N',N'-dimethylpropane-1,3-diamine |
NA |
912010839 |
NA |
NA |
NA |
NA |
BindingDB |