| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TERT |
N,N'-(dibenzo[b,j][1,7]phenanthroline-2,10-diyldimethanediyl)dipropan-1-amine |
NA |
301995172 |
NA |
NA |
NA |
NA |
BindingDB |
| TET1 |
Succinic Acid |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| TET1 |
(2R)-2-hydroxypentanedioic acid |
246000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TET1 |
(2S)-2-hydroxypentanedioic acid |
269000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TET1 |
Fumaric Acid |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| TET1 |
Methyl 2-(2-methoxy-2-oxoacetamido)acetate |
NA |
NA |
NA |
110000 |
NA |
NA |
BindingDB |
| TET1 |
Dimethyl Fumarate |
NA |
NA |
NA |
316000 |
NA |
NA |
BindingDB |
| TET2 |
Succinic Acid |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| TET2 |
2-Hydroxyglutaric acid |
NA |
261500 |
NA |
NA |
NA |
NA |
PubChem |
| TET2 |
Fumaric Acid |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| TET2 |
(2R)-Octyl-alpha-hydroxyglutarate |
NA |
NA |
NA |
131000 |
NA |
NA |
BindingDB |
| TET3 |
Succinic Acid |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| TET3 |
Fumaric Acid |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| TET3 |
Methyl 2-(2-methoxy-2-oxoacetamido)acetate |
NA |
NA |
NA |
177000 |
NA |
NA |
BindingDB |
| TET3 |
(2R)-Octyl-alpha-hydroxyglutarate |
NA |
NA |
NA |
186000 |
NA |
NA |
BindingDB |
| TGFBR1 |
N,N-dimethyl-5-(4-piperazin-1-ylphenyl)-3-(3,4,5-trimethoxyphenyl)pyridin-2-amine |
NA |
115000 |
NA |
NA |
NA |
NA |
TTD |
| TGFBR1 |
4-(4-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one |
950000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TGFBR1 |
4-(4-aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one |
640000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TGFBR1 |
3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)benzamide |
2800000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TGFBR1 |
4-(3-(aminomethyl)phenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one |
2800000 |
NA |
NA |
NA |
NA |
NA |
TTD |