| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TK1 |
Decanoic acid 2-[5-((E)-2-bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl ester |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
6-(4-fluorophenyl)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]furo[2,3-d]pyrimidin-2-one |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
Deoxyguanosine |
NA |
115000|364000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TK1 |
Araguanosine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
9-(2''-O-pentanoyl-beta-D-arabinofuranosyl)guanine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
N2-octanoyl-9-(2''-O-octanoyl-beta-D-arabinofuranosyl)guanine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
9-(2''-O-octanoyl-beta-D-arabinofuranosyl)guanine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
[(2S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)oxolan-2-yl]methyl benzoate |
975000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
Stavudine |
580000|615000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem|TTD |
| TK1 |
|
NA |
115000|364000 |
NA |
NA |
NA |
NA |
BindingDB |
| TK1 |
|
180000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TK1 |
1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-phenylmethoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(4-hydroxyphenyl)furo[2,3-d]pyrimidin-2-one |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
6-[4-(2-fluoroethoxy)phenyl]-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]furo[2,3-d]pyrimidin-2-one |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
6-[3-(6-fluorohexoxy)phenyl]-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]furo[2,3-d]pyrimidin-2-one |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
6-[4-(6-fluorohexoxy)phenyl]-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]furo[2,3-d]pyrimidin-2-one |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
2',3'-Didehydro-3'-deoxy-4-thiothymidine |
1690000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
3'-Deoxy-4-thiothymidine |
1600000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
2',3'-Didehydro-2',3'-dideoxy-4-thiouridine |
1690000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
2',3'-Dideoxy-4-thiouridine |
1275000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |