| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TK1 |
2'',3''-Dideoxy-3''-(2-hydroxyethyldithio)thymidine |
NA |
405000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
2'',3''-Dideoxy-3''-(2-aminoethyldithio)thymidine |
NA |
418000 |
NA |
NA |
NA |
NA |
BindingDB |
| TK1 |
3''-(4-(2-Pyridine)-1,2,3-triazole-1-yl)-2''-deoxythymidine |
NA |
316000 |
NA |
NA |
NA |
NA |
BindingDB |
| TK1 |
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[(2S,3S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2-(trityloxymethyl)oxolan-3-yl]thiourea |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
5-[(E)-2-bromoethenyl]-1-[(2R,4S,5S)-5-(hydroxymethyl)-4-(4-phenyltriazol-1-yl)oxolan-2-yl]pyrimidine-2,4-dione |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
5-[(E)-2-bromoethenyl]-1-[(2R,4S,5S)-4-[4-(4-chlorophenyl)triazol-1-yl]-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
3''-(4-Butyl-1,2,3-triazol-1-yl)-3''-deoxy-beta-D-thymidine |
NA |
366000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
5-[(Z)-2-bromoethenyl]-1-[(3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
1-[(2R,4S,5S)-4-[5-(4-chlorophenyl)triazol-1-yl]-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione |
NA |
109000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[(2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]thiourea |
NA |
316000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
1-[(2R,4S,5S)-4-(4-benzyltriazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione |
NA |
318000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
3''-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3''-deoxy-beta-D-thymidine |
NA |
177000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
3''-(4-(3-Chloro-propyl)-1,2,3-triazol-1-yl)-3''-deoxythymidine |
NA |
105000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
3''-(4-Propyl-1,2,3-triazol-1-yl)-3''-deoxythymidine |
NA |
311000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
3''-(4-tert-Butyl-1,2,3-triazol-1-yl)-3''-deoxythymidine |
NA |
114000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
1-(4-Azidomethyl-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione |
1040000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
1-(4-Fluoromethyl-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione |
970000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TK1 |
Dodecanoic acid 4-hydroxy-5-hydroxymethyl-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
Pentanoic acid 4-hydroxy-5-hydroxymethyl-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TK1 |
1-(3-Benzyloxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |