| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TLR8 |
4-Amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol |
NA |
NA |
NA |
270000 |
NA |
NA |
TTD |
| TLR8 |
Imiquimod |
NA |
NA |
NA |
270000 |
NA |
NA |
PubChem|TTD |
| TLR8 |
6-amino-2-butoxy-9-(4-piperidin-4-ylbutyl)-7H-purin-8-one |
NA |
NA |
NA |
131000 |
NA |
NA |
TTD |
| TLR8 |
6-amino-2-butoxy-9-(3-piperidin-4-ylpropyl)-7H-purin-8-one |
NA |
NA |
NA |
260000 |
NA |
NA |
TTD |
| TLR8 |
6-amino-2-butoxy-9-(2-piperidin-4-ylethyl)-7H-purin-8-one |
NA |
NA |
NA |
231000 |
NA |
NA |
TTD |
| TLR8 |
Methyl 4-amino-1-(2-hydroxy-2-methylpropyl)imidazo[4,5-c]quinoline-7-carboxylate |
NA |
NA |
NA |
270000 |
NA |
NA |
TTD |
| TMPRSS6 |
3-(Benzylsulfamoyl)benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-(Benzylsulfamoyl)benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
2-[(4-carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)acetamide |
115000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TMPRSS6 |
3-[(4-carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]propanamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-(Phenylsulfamoyl)benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(4-carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)propanamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(4-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(3-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(4-carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]butanamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(3-carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)butanamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(3-Methoxyphenyl)sulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(3-carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)propanamide |
132000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TMPRSS6 |
3-[(3-carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]propanamide |
187000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TMPRSS6 |
4-[(3,4-Dimethoxyphenyl)sulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |