| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TMPRSS6 |
3-[(4-Methoxyphenyl)sulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(4-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(3-Methoxyphenyl)sulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(3,4-Dimethoxyphenyl)sulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(3-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
3-[(3,4-Dimethoxyphenyl)methylsulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
2-[(4-carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]acetamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
2-[(3-carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]acetamide |
155000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TMPRSS6 |
4-[(4-carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)butanamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(4-Methoxyphenyl)sulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(3,4-Dimethoxyphenyl)methylsulfamoyl]benzenecarboximidamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
4-[(3-carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]butanamide |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
2-[(3-carbamimidoylphenyl)sulfonylamino]-N-propan-2-ylacetamide;2,2,2-trifluoroacetic acid |
148000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
N-(3-carbamimidoylphenyl)-2-[(3,4-dimethoxyphenyl)sulfonylamino]acetamide;2,2,2-trifluoroacetic acid |
196000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
N-(3-carbamimidoylphenyl)-2-(naphthalen-2-ylsulfonylamino)acetamide;2,2,2-trifluoroacetic acid |
163000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
N-(3-carbamimidoylphenyl)-2-(naphthalen-1-ylsulfonylamino)acetamide;2,2,2-trifluoroacetic acid |
163000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
Tert-butyl 3-[[2-[(4-carbamimidoylphenyl)sulfonylamino]acetyl]amino]benzoate;2,2,2-trifluoroacetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
Tert-butyl 4-[3-[(4-carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoate;2,2,2-trifluoroacetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
Tert-butyl 3-[3-[(4-carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoate;2,2,2-trifluoroacetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TMPRSS6 |
Tert-butyl 3-[4-[(4-carbamimidoylphenyl)sulfonylamino]butanoylamino]benzoate;2,2,2-trifluoroacetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |