| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TMPRSS6 |
[Amino-[3-[[2-[(3,4-dimethoxyphenyl)sulfonylamino]acetyl]amino]phenyl]methylidene]azanium |
196000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TMPRSS6 |
[Amino-[3-[[2-oxo-2-(propan-2-ylamino)ethyl]sulfamoyl]phenyl]methylidene]azanium |
148000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TNF |
4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl)-butyric acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadiazolo[3,4-d]pyrimidin-6-yl)-butyric acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(1-Benzyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl)-butyric acid ethyl ester |
NA |
175000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TNF |
4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl)-butyric acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1-ylmethyl)-benzoic acid methyl ester |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-butyric acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(1-Methyl-2,4-dioxo-6-phenyl-1,4-dihydro-2H-pteridin-3-yl)-butyric acid ethyl ester |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1-ylmethyl)-benzoic acid methyl ester |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
4-(6,7-Diethyl-1-methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl)-butyric acid ethyl ester |
NA |
130000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TNF |
1-(3-Carboxypropyl)-3,7-dimethylxanthine |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
1-[(2,4-Dimethylphenyl)methyl]benzimidazole |
NA |
NA |
106000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| TNF |
3-Methyl-8-sulfanylidene-7,9-dihydropurine-2,6-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
Mesalamine |
NA |
20600000 |
NA |
NA |
NA |
NA |
BindingDB|PubChem|TTD |
| TNF |
4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1-ylmethyl)-benzoic acid ethyl ester |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TNF |
1,3-Dihydro-1,3-dioxo-beta-phenyl-2H-isoindole-2-propanamide |
NA |
260000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TNF |
1-Benzyl-1H-benzimidazole |
NA |
NA|204000 |
300000|NA|3e+05 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| TNF |
(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1-yl)-acetic acid ethyl ester |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| TNF |
1-Benzyl-2-methylbenzimidazole |
NA |
NA |
325000 |
NA |
NA |
NA |
BindingDB|ChEMBL |