| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP1 |
21,22-O-Diangeloyl-3beta,16alpha,28-trihydroxyolean-12-ene |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
2,4-Pyrimidinediamine, 6-chloro-N4-(3,4-dichlorophenyl)- |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Camptothecin |
NA |
127000 |
NA |
NA |
NA |
NA |
PubChem |
| TOP1 |
[(3R,4S,5R)-3,4-dihydroxy-5-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-3-yl]oxyoxolan-3-yl]methyl acetate |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Doxorubicin |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem |
| TOP1 |
Etoposide |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP1 |
Ginsenoside B2 |
NA |
250000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP1 |
2,4,6-Tri-furan-2-yl-pyridine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
4-Furan-2-yl-2-thiophen-2-yl-pyridine |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
6-(1-Hydroxy-propyl)-5,8-dimethoxy-[1,4]naphthoquinone |
NA |
121830 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(3E)-3-[(4-fluorophenyl)methylidene]-1-benzofuran-2-one |
NA |
392000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
ethyl 2-[4-[(E)-(2-oxo-1-benzofuran-3-ylidene)methyl]phenyl]acetate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(3E)-3-[(4-hydroxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(E)-3-(3,4-Dihydroxybenzylidene)benzofuran-2(3H)-one |
NA |
160000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(3E)-3-[(3-hydroxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
262000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(3E)-3-benzylidene-5-hydroxy-1-benzofuran-2-one |
NA |
960000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(3E)-3-[(4-hydroxy-3-methoxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
630000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Gypenoside Xvii |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Ginsenoside-F5 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
2, 3-Dihydroxy-12-ursen-28-oic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |