| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP1 |
Aesculioside IIf |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Aesculioside IIIc |
NA |
131700 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Quinovic acid 28-O-beta-D-glucopyranosyl ester |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
3-O-beta-6-deoxy-D-glucopyranosyl cincholic acid28-O-beta-D-glucopyranosyl ester |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
3-O-alpha-L-rhamnopyranosyl quinovic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-1,2,6b,9,9,12a-hexamethyl-4a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
(1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-4a-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxycarbonyl-1,2,6b,9,9,12a-hexamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
26,27-Dihydroxylanosta-7,9(11),24-trien-3-one |
NA |
106000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
N2-(3,4-dichlorophenyl)-9H-purine-2,6-diamine |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
kaempferol 3-O-beta-D-galactopyranosyl-7-O-alpha-L-rhamnopyranoside |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Kaempferol 3-O-(Alpha-L-Rhamnopyranosyl(1->2)-Beta-D-Galactopyranosyl)-7-O-Alpha-L-Rhamnopyranoside |
NA |
260000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Kaempferol 3-O-Alpha-L-Arabinopyranosyl-7-O-Alpha-L-Rhamnopyranoside |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Reserpine |
NA |
160000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP1 |
Elaidic Acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
alpha-Amyrin |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-3H-benzofuran-2-one |
NA |
307000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Ginsenoside Rb1 |
NA |
250000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP1 |
Ginsenoside F2 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP1 |
Ginsenoside Rg3 |
NA |
250000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
N-[[14-[2-(diethylamino)ethyl]-4-methoxy-8-thia-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-10-yl]methyl]methanesulfonamide |
NA |
NA |
NA |
210000 |
NA |
NA |
TTD |