| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2A |
1-[[2-(Diethylamino)ethyl]amino]-4-[(methylamino)methyl]thioxanthen-9-one |
NA |
NA |
NA |
270000 |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-benzylidene-1-benzofuran-2-one |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
N-[(7S)-1,2-dihydroxy-3-methoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Spermidine |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
Spermine |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
4,6-dichloro-N-[(4-methoxyphenyl)methyl]-1,3,5-triazin-2-amine |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-5-hydroxy-3-[(3,4,5-trihydroxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
120000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-[(3-hydroxy-4-methoxyphenyl)methylidene]-1-benzofuran-2-one |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Ginsenoside Rd |
NA |
250000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2A |
Aesculioside Iv-23D1 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-N-(4-fluorophenyl)-6-(2H-tetrazol-5-ylsulfanylmethyl)-1,3,5-triazine-2,4-diamine |
NA |
337000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
(3E)-3-[(3,4-dihydroxyphenyl)methylidene]-5-hydroxy-1-benzofuran-2-one |
NA |
240000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
4-benzylsulfanyl-2-phenylsulfanyl-2,5-dihydro-1H-1,3,5-triazin-6-one |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[(4-benzylsulfanyl-6-oxo-2,5-dihydro-1H-1,3,5-triazin-2-yl)sulfanyl]acetic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[2-[[4-(Benzylamino)-6-chloro-1,3,5-triazin-2-yl]amino]phenyl]ethanol |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
2-[2-[[4-Chloro-6-[(4-methoxyphenyl)methylamino]-1,3,5-triazin-2-yl]amino]phenyl]ethanol |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
PD-117596 |
NA |
NA |
NA |
340000 |
NA |
NA |
BindingDB|TTD |
| TOP2A |
20(S)-Ginsenoside Rg2 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
Ginsenoside Rb3 |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2A |
{4-Amino-6-[(4-fluorophenyl)amino]-1,3,5-triazin-2-yl}methyl 4-methylpiperazine-1-carbodithioate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |