| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TOP2B |
Cholestanol |
NA |
500000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TOP2B |
2-[(3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethylhexyl)-10,13-dimethylhexadecahydrocyclopenta[a]phenanthren-3-yloxy]ethanol |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2B |
Quinizarin |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2B |
1-[[(3S,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]ethane-1,2-diol |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2B |
2-[(3S,10R,13R,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxy]-ethanol |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| TOP2B |
(2-(Diethylamino)ethy]-9-methoxy-2H-[1]-benzothiopyrano[4,3,2-cd]indazole-5-methanamine |
NA |
NA |
NA |
260000 |
NA |
NA |
TTD |
| TOP2B |
Formamide, N-((1-((2-(diethylamino)ethyl)amino)-7-methoxy-9-oxo-9H-thioxanthen-4-yl)methyl)- |
NA |
NA |
NA |
480000 |
NA |
NA |
TTD |
| TOP2B |
methyl N-[[1-[[2-(diethylamino)ethyl]amino]-7-methoxy-9-oxothioxanthen-4-yl]methyl]carbamate |
NA |
NA |
NA |
220000 |
NA |
NA |
TTD |
| TOP2B |
2-[2-[Hydroxy-[1-(2-phenyl-1-benzofuran-5-yl)ethyl]carbamoyl]phenyl]benzoic acid |
NA |
121000 |
NA |
NA |
NA |
NA |
BindingDB |
| TP53 |
5-(4-Fluorophenyl)-3-iodanyl-2-oxidanyl-4-pyrrol-1-yl-benzoic acid |
NA |
NA |
113000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
3-Iodanyl-2-oxidanyl-5-(2-phenylethoxy)-4-pyrrol-1-yl-benzoic acid |
NA |
NA |
116000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
6-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-one hydrazone |
NA |
NA |
105000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
2-Hydroxy-3-iodo-5-(4-methoxyphenyl)-4-pyrrol-1-ylbenzoic acid |
NA |
NA |
122000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
2-Hydroxy-3-iodo-4-pyrrol-1-yl-5-(3,3,3-trifluoropropoxy)benzoic acid |
NA |
NA |
108000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
2-Hydroxy-3-iodo-5-phenyl-4-pyrrol-1-ylbenzoic acid |
NA |
NA |
306000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
2-Hydroxy-5-(2-hydroxyethoxy)-3-iodo-4-pyrrol-1-ylbenzoic acid |
NA |
NA |
726000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
N,2-dihydroxy-3,5-diiodo-4-pyrrol-1-ylbenzamide |
NA |
NA |
139000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
[2-[(9-Ethylcarbazol-3-yl)amino]-2-oxoethyl] 5-oxopyrrolidine-2-carboxylate |
NA |
NA |
213000 |
NA |
NA |
NA |
BindingDB |
| TP53 |
Benzophenone |
NA |
NA |
NA |
NA |
114931 |
NA |
PubChem |
| TP53 |
Phenoxyethanol |
NA |
NA |
NA |
NA |
1412540 |
NA |
PubChem |