| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| AMD1 |
(2S,4S)-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]pyrrolidine-2-carboxylic acid;sulfuric acid |
478000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
(2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(pyrrolidin-3-ylsulfanylmethyl)oxolane-3,4-diol;sulfuric acid |
415000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
(2S,4R)-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]pyrrolidine-2-carboxylic acid;sulfuric acid |
960000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]butanenitrile |
NA |
178600 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
2-amino-5-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]pentanenitrile |
NA |
204800 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
4-N-(3,5-dichlorophenyl)-6-morpholin-4-ylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3-chloro-5-naphthalen-2-ylphenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3,5-dichlorophenyl)-6-methylpyridine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3-bromo-5-chlorophenyl)-2-methylpyrimidine-4,6-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-(1-benzothiophen-2-yl)-5-chlorophenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3-bromo-5-butoxyphenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-chloro-5-(4-methoxyphenyl)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3,5-dichlorophenyl)-4-N,6-dimethylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
2-[(2-Amino-6-methylpyrimidin-4-yl)amino]-4,6-dichlorophenol |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3,5-dichloro-4-phenoxyphenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-bromo-5-(pentafluoro-lambda6-sulfanyl)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3,5-dichloro-4-piperidin-1-ylphenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-chloro-5-(4-phenylphenyl)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
6-methyl-4-N-[3-(pentafluoro-lambda6-sulfanyl)phenyl]pyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3,5-dichloro-4-morpholin-4-ylphenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |