| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| AMD1 |
4-N-(3,5-dichlorophenyl)-6-propan-2-ylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
2-N-(3,5-dichlorophenyl)-6-methylpyridine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-chloro-5-(1-methylpyrazol-4-yl)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-chloro-5-(pentafluoro-lambda6-sulfanyl)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3-chloro-5-[4-(dimethylamino)phenyl]phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[3,5-dichloro-4-(dimethylamino)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[(3,5-dichlorophenyl)methyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-[4-(3,5-dichlorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
N-(3,5-dimethylphenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
N~4~-(2,5-dichlorophenyl)-6-methyl-2,4-pyrimidinediamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-(3-Chlorophenylamino)-6-methylpyrimidin-2-amine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(2-bromophenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
(2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-9-yl]-5-{[(3-aminopropyl)(methyl)amino]methyl}oxolane-3,4-diol |
NA |
440000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(3-aminopropyl)(methyl)amino]methyl}oxolane-3,4-diol |
NA |
500000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| AMD1 |
(2R,3R,4S,5R)-2-(6-amino-8-ethyl-9H-purin-9-yl)-5-{[(3-aminopropyl)(methyl)amino]methyl}oxolane-3,4-diol |
NA |
420000 |
NA |
NA |
NA |
NA |
BindingDB |
| AMD1 |
3-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylamino]-N'-hydroxypropanimidamide |
NA |
157000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
3-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)amino)-N''-hydroxypropanimidamide |
NA |
157000 |
NA |
NA |
NA |
NA |
BindingDB |
| AMD1 |
N4-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
4-N-(3,5-dichlorophenyl)pyridine-3,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |
| AMD1 |
6-chloro-N4-(3,5-dichlorophenyl)pyrimidine-2,4-diamine |
NA |
180000 |
NA |
NA |
NA |
NA |
TTD |